Sequence Detail

ID/Version

Q8BWM0 Q99J30 A2ASQ2 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Prostaglandin E synthase 2; EC=5.3.99.3 {ECO:0000250|UniProtKB:Q9H7Z7};AltName: Full=GATE-binding factor 1 {ECO:0000303|PubMed:12050152}; Short=GBF-1 {ECO:0000303|PubMed:12050152};AltName: Full=Microsomal prostaglandin E synt

Provider

SWISS-PROT

Sequence

Polypeptide 384 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ptges2	prostaglandin E synthase 2	22	98	3	13

Sequence references in MGI

J:78558 Hu J, et al., A novel transactivating factor that regulates interferon-gamma-dependent gene expression. J Biol Chem. 2002 Aug 16;277(33):30253-63
J:85658 Murakami M, et al., Cellular prostaglandin E2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2. J Biol Chem. 2003 Sep 26;278(39):37937-47
J:99017 Meng Q, et al., IFN-gamma-stimulated transcriptional activation by IFN-gamma-activated transcriptional element-binding factor 1 occurs via an inducible interaction with CAAAT/enhancer-binding protein-beta. J Immunol. 2005 May 15;174(10):6203-11
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:107865 Bosetti F, et al., Prostaglandin E2 and microsomal prostaglandin E synthase-2 expression are decreased in the cyclooxygenase-2-deficient mouse brain despite compensatory induction of cyclooxygenase-1 and Ca2+-dependent phospholipase A2. J Neurochem. 2004 Dec;91(6):1389-97
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89