Sequence Detail

ID/Version

Q8BXK9 Q3U0H8 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Chloride intracellular channel protein 5;AltName: Full=Glutaredoxin-like oxidoreductase CLIC5 {ECO:0000250|UniProtKB:O00299}; EC=1.8.-.- {ECO:0000250|UniProtKB:O00299};

Provider

SWISS-PROT

Sequence

Polypeptide 251 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Clic5	chloride intracellular channel 5	38	108	4	11

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:112741 Gagnon LH, et al., The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function. J Neurosci. 2006 Oct 4;26(40):10188-98
J:269554 Fan J, et al., The klotho-related protein KLPH (lctl) has preferred expression in lens and is essential for expression of clic5 and normal lens suture formation. Exp Eye Res. 2018 Apr;169:111-121
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:318211 Salles FT, et al., CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI. Cytoskeleton (Hoboken). 2014 Jan;71(1):61-78
J:345440 Qi J, et al., Critical role of TPRN rings in the stereocilia for hearing. Mol Ther. 2024 Jan 3;32(1):204-217