Sequence Detail

ID/Version

Q8C503 Q9WUU5 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Signaling threshold-regulating transmembrane adapter 1;AltName: Full=SHP2-interacting transmembrane adapter protein;AltName: Full=Suppression-inducing transmembrane adapter 1;

Provider

SWISS-PROT

Sequence

Polypeptide 180 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sit1	suppression inducing transmembrane adaptor 1	12	96	2	7

Sequence references in MGI

J:62650 Marie-Cardine A, et al., SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation. J Exp Med. 1999 Apr 19;189(8):1181-94
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100408 Simeoni L, et al., The transmembrane adapter protein SIT regulates thymic development and peripheral T-cell functions. Mol Cell Biol. 2005 Sep;25(17):7557-68
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89