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Sequence Detail
ID/Version
Q8C9J3 G0Z098 A2RSG5 E0CYG3 (UniProt | EBI) Last sequence update: 2018-10-10
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Sperm flagellar protein 2;AltName: Full=Protein KPL2;
Provider SWISS-PROT
Sequence
Polypeptide 1724 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Spef2 sperm flagellar 2 30 96 3 5
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:159553 Sironen A, et al., Expression of SPEF2 during mouse spermatogenesis and identification of IFT20 as an interacting protein. Biol Reprod. 2010 Mar;82(3):580-90
J:176695 Sironen A, et al., Loss of SPEF2 Function in Mice Results in Spermatogenesis Defects and Primary Ciliary Dyskinesia. Biol Reprod. 2011 Oct;85(4):690-701
J:242894 Lehti MS, et al., SPEF2 functions in microtubule-mediated transport in elongating spermatids to ensure proper male germ cell differentiation. Development. 2017 Jul 15;144(14):2683-2693
J:264497 Lehti MS, et al., Cilia-related protein SPEF2 regulates osteoblast differentiation. Sci Rep. 2018 Jan 16;8(1):859

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory