Sequence Detail

ID/Version

Q8CBC7 A2ALH2 Q8JZY1 Q91XA6 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase {ECO:0000305}; EC=2.1.1.205 {ECO:0000255|HAMAP-Rule:MF_03162};AltName: Full=2'-O-ribose RNA methyltransferase TRM7 homolog {ECO:0000255|HAMAP-Rule:MF_03162};AltName: Full=Prote

Provider

SWISS-PROT

Sequence

Polypeptide 324 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ftsj1	FtsJ RNA 2'-O-methyltransferase 1	23	97	3	26

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:277318 Jensen LR, et al., A mouse model for intellectual disability caused by mutations in the X-linked 2'Omethyltransferase Ftsj1 gene. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2083-2093
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:328916 Nagayoshi Y, et al., Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability. Sci Adv. 2021 Mar;7(13)