Sequence Detail

ID/Version

Q8CCH7 Q9Z0F2 (UniProt | EBI)

Last sequence update: 2004-03-15
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Zinc finger protein ZFPM2;AltName: Full=Friend of GATA protein 2; Short=FOG-2; Short=Friend of GATA 2; Short=mFOG-2;AltName: Full=Zinc finger protein multitype 2;

Provider

SWISS-PROT

Sequence

Polypeptide 1151 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Zfpm2	zinc finger protein, multitype 2	63	130	4	17

Sequence references in MGI

J:52532 Tevosian SG, et al., FOG-2: A novel GATA-family cofactor related to multitype zinc-finger proteins Friend of GATA-1 and U-shaped. Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):950-5
J:53717 Svensson EC, et al., Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes. Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):956-61
J:55073 Lu JR, et al., FOG-2, a heart- and brain-enriched cofactor for GATA transcription factors. Mol Cell Biol. 1999 Jun;19(6):4495-502
J:62879 Tevosian SG, et al., FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium. Cell. 2000 Jun 23;101(7):729-39
J:63121 Svensson EC, et al., A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2. Nat Genet. 2000 Jul;25(3):353-6
J:70599 Huggins GS, et al., Friend of GATA 2 physically interacts with chicken ovalbumin upstream promoter-TF2 (COUP-TF2) and COUP-TF3 and represses COUP-TF2-dependent activation of the atrial natriuretic factor promoter. J Biol Chem. 2001 Jul 27;276(30):28029-36
J:78688 Tevosian SG, et al., Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2. Development. 2002 Oct;129(19):4627-34
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:203454 Rawnsley DR, et al., The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development. J Biol Chem. 2013 Aug 23;288(34):24429-40