Sequence Detail

ID/Version

Q8CDJ3 Q8C6N0 Q69ZY1 Q6PFY6 Q8R3M3 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Beclin 1-associated autophagy-related key regulator {ECO:0000250|UniProtKB:Q6ZNE5}; Short=Barkor {ECO:0000250|UniProtKB:Q6ZNE5};AltName: Full=Autophagy-related protein 14-like protein {ECO:0000303|PubMed:19270696}; Short=Atg1

Provider

SWISS-PROT

Sequence

Polypeptide 492 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Atg14	autophagy related 14	66	97	3	21

Sequence references in MGI

J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:158180 Matsunaga K, et al., Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat Cell Biol. 2009 Apr;11(4):385-96
J:166673 Dou Z, et al., The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy. J Cell Biol. 2010 Nov 15;191(4):827-43
J:192959 Xiong X, et al., The autophagy-related gene 14 (Atg14) is regulated by forkhead box O transcription factors and circadian rhythms and plays a critical role in hepatic autophagy and lipid metabolism. J Biol Chem. 2012 Nov 9;287(46):39107-14
J:203423 Pampliega O, et al., Functional interaction between autophagy and ciliogenesis. Nature. 2013 Oct 10;502(7470):194-200
J:219056 Kim J, et al., Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy. Cell. 2013 Jan 17;152(1-2):290-303
J:219088 Zhong Y, et al., Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol. 2009 Apr;11(4):468-76
J:220500 Lu J, et al., NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity. Nat Commun. 2014;5:3920
J:308934 Lei Y, et al., Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility. Dev Cell. 2021 Aug 23;56(16):2313-2328.e7