Sequence Detail

ID/Version

Q8CEE6 E9QM58 Q91YD8 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=PAS domain-containing serine/threonine-protein kinase; Short=PAS-kinase; Short=PASKIN; EC=2.7.11.1;

Provider

SWISS-PROT

Sequence

Polypeptide 1383 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pask	PAS domain containing serine/threonine kinase	50	99	3	13

Sequence references in MGI

J:72611 Hofer T, et al., Mammalian PASKIN, a PAS-Serine/Threonine Kinase Related to Bacterial Oxygen Sensors. Biochem Biophys Res Commun. 2001 Nov 9;288(4):757-64
J:85762 Katschinski DM, et al., Targeted disruption of the mouse PAS domain serine/threonine kinase PASKIN. Mol Cell Biol. 2003 Oct;23(19):6780-9
J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121974 Borter E, et al., Glucose-stimulated insulin production in mice deficient for the PAS kinase PASKIN. Diabetes. 2007 Jan;56(1):113-7
J:125307 Hao HX, et al., PAS kinase is required for normal cellular energy balance. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15466-71
J:139216 Soliz J, et al., Ventilatory responses to acute and chronic hypoxia are altered in female but not male Paskin-deficient mice. Am J Physiol Regul Integr Comp Physiol. 2008 Aug;295(2):R649-58
J:167207 da Silva Xavier G, et al., Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion. Diabetologia. 2011 Apr;54(4):819-27
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89