Sequence Detail

ID/Version

Q8CFE3 Q8CHI2 Q8BK28 K3W4P9 Q3V092 (UniProt | EBI)

Last sequence update: 2017-02-15
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=REST corepressor 1;AltName: Full=Protein CoREST;

Provider

SWISS-PROT

Sequence

Polypeptide 480 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rcor1	REST corepressor 1	28	107	3	22

Sequence references in MGI

J:61357 Grimes JA, et al., The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex. J Biol Chem. 2000 Mar 31;275(13):9461-7
J:86755 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2002 Oct 31;9(5):179-88
J:98945 Ballas N, et al., REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell. 2005 May 20;121(4):645-57
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:164132 Ravanpay AC, et al., Transcriptional inhibition of REST by NeuroD2 during neuronal differentiation. Mol Cell Neurosci. 2010 Jun;44(2):178-89
J:175166 Saleque S, et al., Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1. Mol Cell. 2007 Aug 17;27(4):562-72
J:206319 Welcker JE, et al., Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors. Development. 2013 Dec;140(24):4947-58
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:331350 Zhang C, et al., Proteolysis of methylated SOX2 protein is regulated by L3MBTL3 and CRL4(DCAF5) ubiquitin ligase. J Biol Chem. 2019 Jan 11;294(2):476-489