Sequence Detail

ID/Version

Q8CHS7 B1ATJ2 (UniProt | EBI)

Last sequence update: 2008-05-20
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Dehydrogenase/reductase SDR family member 7C {ECO:0000303|PubMed:29330505}; EC=1.1.1.105 {ECO:0000269|PubMed:21995425};AltName: Full=Sarcoplasmic reticulum protein of 35 kDa {ECO:0000303|PubMed:21995425}; Short=Protein SRP-35

Provider

SWISS-PROT

Sequence

Polypeptide 311 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dhrs7c	dehydrogenase/reductase 7C	9	96	4	6

Sequence references in MGI

J:180629 Treves S, et al., SRP-35, a newly identified protein of the skeletal muscle sarcoplasmic reticulum, is a retinol dehydrogenase. Biochem J. 2012 Jan 15;441(2):731-41
J:260197 Ruiz A, et al., Over-expression of a retinol dehydrogenase (SRP35/DHRS7C) in skeletal muscle activates mTORC2, enhances glucose metabolism and muscle performance. Sci Rep. 2018 Jan 12;8(1):636
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:313956 Arai S, et al., Functional loss of DHRS7C induces intracellular Ca2+ overload and myotube enlargement in C2C12 cells via calpain activation. Am J Physiol Cell Physiol. 2017 Jan 1;312(1):C29-C39
J:314216 Lu B, et al., DHRS7c, a novel cardiomyocyte-expressed gene that is down-regulated by adrenergic stimulation and in heart failure. Eur J Heart Fail. 2012 Jan;14(1):5-13