ID/Version |
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Sequence description from provider |
RecName: Full=Protein arginine N-methyltransferase 5; Short=Prmt5; EC=2.1.1.320 {ECO:0000269|PubMed:28263986};AltName: Full=Histone-arginine N-methyltransferase PRMT5;AltName: Full=Jak-binding protein 1;AltName: Full=Shk1 kinase-binding pr | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
637
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:58151
Pollack BP, et al., The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity. J Biol Chem. 1999 Oct 29;274(44):31531-42
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:109626 Ancelin K, et al., Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. Nat Cell Biol. 2006 Jun;8(6):623-30 J:151086 Vagin VV, et al., Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members. Genes Dev. 2009 Aug 1;23(15):1749-62 J:156247 van Dijk TB, et al., Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases. Mol Cell Biol. 2010 Jan;30(1):260-72 J:192252 Na J, et al., Role of type II protein arginine methyltransferase 5 in the regulation of Circadian Per1 gene. PLoS One. 2012;7(10):e48152 J:196248 Paul C, et al., The histone- and PRMT5-associated protein COPR5 is required for myogenic differentiation. Cell Death Differ. 2012 May;19(5):900-8 J:242066 Akpinar M, et al., TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes. PLoS Genet. 2017 Mar;13(3):e1006660 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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