ID/Version |
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Sequence description from provider |
RecName: Full=Ankyrin repeat and SOCS box protein 2; Short=ASB-2; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
634
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:66288
Kile BT, et al., Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins asb-1, asb-2, asb-3 and asb-4. Gene. 2000 Nov 27;258(1-2):31-41
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:164183 Bello NF, et al., The E3 ubiquitin ligase specificity subunit ASB2beta is a novel regulator of muscle differentiation that targets filamin B to proteasomal degradation. Cell Death Differ. 2009 Jun;16(6):921-32 J:200966 Lamsoul I, et al., ASB2alpha regulates migration of immature dendritic cells. Blood. 2013 Jul 25;122(4):533-41 J:251576 Thottakara T, et al., The E3 ubiquitin ligase Asb2beta is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation. J Mol Cell Cardiol. 2015 Oct;87:214-24 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 J:306591 Davey JR, et al., Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass. JCI Insight. 2016 Apr 21;1(5):e85477 J:306640 Yamak A, et al., Loss of Asb2 Impairs Cardiomyocyte Differentiation and Leads to Congenital Double Outlet Right Ventricle. iScience. 2020 Mar 27;23(3):100959 J:306706 Metais A, et al., Asb2alpha-Filamin A Axis Is Essential for Actin Cytoskeleton Remodeling During Heart Development. Circ Res. 2018 Mar 16;122(6):e34-e48 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/05/2024 MGI 6.24 |
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