ID/Version |
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Sequence description from provider |
RecName: Full=Nuclear factor of activated T-cells, cytoplasmic 4 {ECO:0000250|UniProtKB:Q14934}; Short=NF-ATc4 {ECO:0000250|UniProtKB:Q14934}; Short=NFATc4 {ECO:0000303|PubMed:18354019};AltName: Full=T-cell transcription factor NFAT3 {ECO: | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
901
aa
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Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:79608
Wilkins BJ, et al., Targeted Disruption of NFATc3, but Not NFATc4, Reveals an Intrinsic Defect in Calcineurin-Mediated Cardiac Hypertrophic Growth. Mol Cell Biol. 2002 Nov;22(21):7603-13
J:84138 Bushdid PB, et al., NFATc3 and NFATc4 are required for cardiac development and mitochondrial function. Circ Res. 2003 Jun 27;92(12):1305-13 J:93176 Molkentin JD, et al., A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell. 1998 May 17;93(2):215-28 J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:119549 Yang XY, et al., Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 J:133209 Luoma JI, et al., Deafferentation-induced activation of NFAT (nuclear factor of activated T-cells) in cochlear nucleus neurons during a developmental critical period: a role for NFATc4-dependent apoptosis in the CNS. J Neurosci. 2008 Mar 19;28(12):3159-69 J:139569 Wang D, et al., The interleukin-1 receptor associated kinase 1 contributes to the regulation of NFAT. Mol Immunol. 2008 Sep;45(15):3902-8 J:141917 Cante-Barrett K, et al., Selective role of NFATc3 in positive selection of thymocytes. J Immunol. 2007 Jul 1;179(1):103-10 J:141959 Vihma H, et al., Alternative splicing and expression of human and mouse NFAT genes. Genomics. 2008 Nov;92(5):279-91 J:169854 Reddy RN, et al., Rescue of Calcineurin Aalpha(-/-) Mice Reveals a Novel Role for the alpha Isoform in the Salivary Gland. Am J Pathol. 2011 Apr;178(4):1605-13 J:184759 Quadrato G, et al., Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):E1499-508 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 J:343111 Ranjan R, et al., The transcription factor nuclear factor of activated T cells c3 modulates the function of macrophages in sepsis. J Innate Immun. 2014;6(6):754-64 J:343388 Manukyan I, et al., Cross-talk between calcineurin/NFAT and Jak/STAT signalling induces cardioprotective alphaB-crystallin gene expression in response to hypertrophic stimuli. J Cell Mol Med. 2010 Jun;14(6B):1707-16 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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