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Sequence Detail
ID/Version
Q8K4B2 Q8K1S8 Q8C7U8 Q8CE40 (UniProt | EBI) Last sequence update: 2004-10-25
Last annotation update: 2024-11-27
Sequence
description
from provider
RecName: Full=Interleukin-1 receptor-associated kinase 3; Short=IRAK-3;AltName: Full=IL-1 receptor-associated kinase M; Short=IRAK-M;AltName: Full=Inactive IL-1 receptor-associated kinase 3 {ECO:0000305};
Provider SWISS-PROT
Sequence
Polypeptide 609 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Irak3 interleukin-1 receptor-associated kinase 3 64 96 3 41
Sequence references in MGI J:77382 Rosati O, et al., Identification and characterization of murine IRAK-M. Biochem Biophys Res Commun. 2002 May 24;293(5):1472-7
J:78189 Kobayashi K, et al., IRAK-M is a negative regulator of Toll-like receptor signaling. Cell. 2002 Jul 26;110(2):191-202
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:304047 Nechama M, et al., The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation. Nat Commun. 2018 Apr 23;9(1):1603

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory