Sequence Detail

ID/Version

Q8K4B2 Q8C7U8 Q8K1S8 Q8CE40 (UniProt | EBI)

Last sequence update: 2004-10-25
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Interleukin-1 receptor-associated kinase 3; Short=IRAK-3;AltName: Full=IL-1 receptor-associated kinase M; Short=IRAK-M;AltName: Full=Inactive IL-1 receptor-associated kinase 3 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 609 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Irak3	interleukin-1 receptor-associated kinase 3	64	96	3	41

Sequence references in MGI

J:77382 Rosati O, et al., Identification and characterization of murine IRAK-M. Biochem Biophys Res Commun. 2002 May 24;293(5):1472-7
J:78189 Kobayashi K, et al., IRAK-M is a negative regulator of Toll-like receptor signaling. Cell. 2002 Jul 26;110(2):191-202
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:304047 Nechama M, et al., The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation. Nat Commun. 2018 Apr 23;9(1):1603