Sequence Detail

ID/Version

Q8K4C2 G3X9C0 Q99J43 (UniProt | EBI)

Last sequence update: 2016-03-16
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Interleukin-17 receptor C; Short=IL-17 receptor C; Short=IL-17RC;AltName: Full=Interleukin-17 receptor-like protein; Short=IL-17RL;AltName: Full=ZcytoR14;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 698 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Il17rc	interleukin 17 receptor C	16	97	4	12

Sequence references in MGI

J:143719 Ishigame H, et al., Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity. 2009 Jan;30(1):108-19
J:153022 Kuestner RE, et al., Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F. J Immunol. 2007 Oct 15;179(8):5462-73
J:161934 Ho AW, et al., IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail. J Immunol. 2010 Jul 15;185(2):1063-70
J:246922 Wang X, et al., IL-17A Promotes Pulmonary B-1a Cell Differentiation via Induction of Blimp-1 Expression during Influenza Virus Infection. PLoS Pathog. 2016 Jan;12(1):e1005367
J:251827 De Luca A, et al., The IL-17F/IL-17RC Axis Promotes Respiratory Allergy in the Proximal Airways. Cell Rep. 2017 Aug 15;20(7):1667-1680
J:266885 Chen K, et al., IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae. Cell Host Microbe. 2016 Nov 9;20(5):596-605
J:292764 Hu B, et al., gammadelta T cells and adipocyte IL-17RC control fat innervation and thermogenesis. Nature. 2020 Feb;578(7796):610-614