Sequence Detail

ID/Version

Q8R0W0 (UniProt | EBI)

Last sequence update: 2003-08-15
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Epiplakin {ECO:0000303|PubMed:12791695};

Provider

SWISS-PROT

Sequence

Polypeptide 6548 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Eppk1	epiplakin 1	44	8	2	9

Sequence references in MGI

J:85100 Spazierer D, et al., Epiplakin gene analysis in mouse reveals a single exon encoding a 725-kDa protein with expression restricted to epithelial tissues. J Biol Chem. 2003 Aug 22;278(34):31657-66
J:138481 Spazierer D, et al., Stress-induced recruitment of epiplakin to keratin networks increases their resistance to hyperphosphorylation-induced disruption. J Cell Sci. 2008 Mar 15;121(Pt 6):825-33
J:144147 Goto M, et al., Elimination of epiplakin by gene targeting results in acceleration of keratinocyte migration in mice. Mol Cell Biol. 2006 Jan;26(2):548-58
J:215291 Kokado M, et al., Increased fragility, impaired differentiation, and acceleration of migration of corneal epithelium of epiplakin-null mice. Invest Ophthalmol Vis Sci. 2013 May;54(5):3780-9
J:220637 Wogenstein KL, et al., Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules. PLoS One. 2014;9(9):e108323
J:236209 Szabo S, et al., Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization. J Hepatol. 2015 Jun;62(6):1357-66
J:237683 Ishikawa K, et al., Epiplakin accelerates the lateral organization of keratin filaments during wound healing. J Dermatol Sci. 2010 Nov;60(2):95-104