Sequence Detail

ID/Version

Q8R1B0 Q8BV93 Q8K2U4 (UniProt | EBI)

Last sequence update: 2002-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=SH3 and cysteine-rich domain-containing protein 2;AltName: Full=24b2/STAC2 {ECO:0000303|Ref.1};AltName: Full=Src homology 3 and cysteine-rich domain-containing protein 2;

Provider

SWISS-PROT

Sequence

Polypeptide 408 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Stac2	SH3 and cysteine rich domain 2	8	99	2	7

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:218374 Polster A, et al., Stac adaptor proteins regulate trafficking and function of muscle and neuronal L-type Ca2+ channels. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):602-6
J:222015 Nelson BR, et al., Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11881-6
J:252007 Campiglio M, et al., STAC3 stably interacts through its C1 domain with CaV1.1 in skeletal muscle triads. Sci Rep. 2017 Jan 23;7:41003
J:261962 Polster A, et al., Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of CaV1.1. J Gen Physiol. 2018 Apr 2;150(4):613-624
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89