Sequence Detail

ID/Version

Q8R429 (UniProt | EBI)

Last sequence update: 2002-06-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Sarcoplasmic/endoplasmic reticulum calcium ATPase 1; Short=SERCA1; Short=SR Ca(2+)-ATPase 1; EC=7.2.2.10 {ECO:0000269|PubMed:21697544, ECO:0000269|PubMed:26816378};AltName: Full=Calcium pump 1;AltName: Full=Calcium-tr

Provider

SWISS-PROT

Sequence

Polypeptide 994 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	75	120	4	5

Sequence references in MGI

J:177617 Tupling AR, et al., Enhanced Ca2+ transport and muscle relaxation in skeletal muscle from sarcolipin-null mice. Am J Physiol Cell Physiol. 2011 Oct;301(4):C841-9
J:193427 Bal NC, et al., Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals. Nat Med. 2012 Oct;18(10):1575-9
J:217579 Anderson DM, et al., A micropeptide encoded by a putative long noncoding RNA regulates muscle performance. Cell. 2015 Feb 12;160(4):595-606
J:229305 Nelson BR, et al., A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle. Science. 2016 Jan 15;351(6270):271-5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89