Sequence Detail

ID/Version

Q8R4D5 E9Q165 Q148W9 (UniProt | EBI)

Last sequence update: 2013-02-06
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Transient receptor potential cation channel subfamily M member 8;AltName: Full=Long transient receptor potential channel 6; Short=LTrpC-6; Short=LTrpC6;AltName: Full=Transient receptor potential p8; Short=Trp-p8;

Provider

SWISS-PROT

Sequence

Polypeptide 1104 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Trpm8	transient receptor potential cation channel, subfamily M, member 8	29	107	2	18

Sequence references in MGI

J:76188 Peier AM, et al., A TRP channel that senses cold stimuli and menthol. Cell. 2002 Mar 8;108(5):705-15
J:96171 Story GM, et al., ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell. 2003 Mar 21;112(6):819-29
J:117484 Dragoni I, et al., The cold and menthol receptor TRPM8 contains a functionally important double cysteine motif. J Biol Chem. 2006 Dec 8;281(49):37353-60
J:122963 Dhaka A, et al., TRPM8 is required for cold sensation in mice. Neuron. 2007 May 3;54(3):371-8
J:148815 Morenilla-Palao C, et al., Lipid raft segregation modulates TRPM8 channel activity. J Biol Chem. 2009 Apr 3;284(14):9215-24
J:224925 Quallo T, et al., TRPM8 is a neuronal osmosensor that regulates eye blinking in mice. Nat Commun. 2015;6:7150