Sequence Detail

ID/Version

Q8R4G6 (UniProt | EBI)

Last sequence update: 2002-06-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; EC=2.4.1.155 {ECO:0000269|PubMed:10700233, ECO:0000269|PubMed:12122020};AltName: Full=Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase;AltName: Full=Glc

Provider

SWISS-PROT

Sequence

Polypeptide 740 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mgat5	mannoside acetylglucosaminyltransferase 5	26	102	3	31

Sequence references in MGI

J:60960 Granovsky M, et al., Suppression of tumor growth and metastasis in Mgat5-deficient mice. Nat Med. 2000 Mar;6(3):306-12
J:87101 Guo HB, et al., N-acetylglucosaminyltransferase V expression levels regulate cadherin-associated homotypic cell-cell adhesion and intracellular signaling pathways. J Biol Chem. 2003 Dec 26;278(52):52412-24
J:93100 Partridge EA, et al., Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis. Science. 2004 Oct 1;306(5693):120-4
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:111264 Demetriou M, et al., Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation. Nature. 2001 Feb 8;409(6821):733-9
J:188930 Lee JK, et al., Developmental expression of the neuron-specific N-acetylglucosaminyltransferase Vb (GnT-Vb/IX) and identification of its in vivo glycan products in comparison with those of its paralog, GnT-V. J Biol Chem. 2012 Aug 17;287(34):28526-36