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Sequence Detail
ID/Version
Q8R550 Q9DC14 Q8CEF6 Q8R551 Q8R547 Q8R549 B1AZ86 Q9CTQ9 Q9JKC3 Q8R548 B1AZ87 Q8CAL8 Q8R545 Q8R546 (UniProt | EBI) Last sequence update: 2002-06-01
Last annotation update: 2024-11-27
Sequence
description
from provider
RecName: Full=SH3 domain-containing kinase-binding protein 1;AltName: Full=Regulator of ubiquitous kinase; Short=Ruk;AltName: Full=SH3-containing, expressed in tumorigenic astrocytes;
Provider SWISS-PROT
Sequence
Polypeptide 709 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Sh3kbp1 SH3-domain kinase binding protein 1 32 98 3 7
Sequence references in MGI J:64312 Hyatt MA, et al., Assignment of seta to distal mouse X chromosome by radiation hybrid mapping. Cytogenet Cell Genet. 2000;89(3-4):278
J:76181 Borinstein SC, et al., SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins. Cell Signal. 2000 Dec;12(11-12):769-79
J:79823 Buchman VL, et al., Organization of the mouse Ruk locus and expression of isoforms in mouse tissues. Gene. 2002 Jul 24;295(1):13-17
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:227464 Feng L, et al., SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex. Cell Biochem Funct. 2011 Oct;29(7):589-96
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory