Sequence Detail

ID/Version

Q8VI67 Q8C5R3 Q8C6A7 (UniProt | EBI)

Last sequence update: 2002-03-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Transcription factor Sp7;AltName: Full=C22;AltName: Full=Zinc finger protein osterix;

Provider

SWISS-PROT

Sequence

Polypeptide 428 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sp7	Sp7 transcription factor 7	41	160	3	21

Sequence references in MGI

J:74344 Nakashima K, et al., The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002 Jan 11;108(1):17-29
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:124618 Xing W, et al., Nuclear factor-E2-related factor-1 mediates ascorbic acid induction of osterix expression via interaction with antioxidant-responsive element in bone cells. J Biol Chem. 2007 Jul 27;282(30):22052-61
J:156025 Sinha KM, et al., Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase. EMBO J. 2010 Jan 6;29(1):68-79
J:266247 Fukuda M, et al., SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix. Nat Commun. 2018 Jul 19;9(1):2833