Sequence Detail

ID/Version

Q8VIG6 O08854 Q922M8 Q9CPP4 (UniProt | EBI)

Last sequence update: 2003-05-09
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:17544371, ECO:0000269|PubMed:22945920};AltName: Full=TRAF-interacting protein {ECO:0000303|PubMed:9104814};

Provider

SWISS-PROT

Sequence

Polypeptide 470 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Traip	TRAF-interacting protein	33	101	3	10

Sequence references in MGI

J:39510 Lee SY, et al., TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation. J Exp Med. 1997 Apr 7;185(7):1275-85
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:127324 Park ES, et al., Early embryonic lethality caused by targeted disruption of the TRAF-interacting protein (TRIP) gene. Biochem Biophys Res Commun. 2007 Nov 30;363(4):971-7
J:206918 Besse A, et al., TRAF-interacting protein (TRIP) is a RING-dependent ubiquitin ligase. Biochem Biophys Res Commun. 2007 Aug 3;359(3):660-4
J:219064 Zhang M, et al., TRAF-interacting protein (TRIP) negatively regulates IFN-beta production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1. J Exp Med. 2012 Sep 24;209(10):1703-11