Sequence Detail

ID/Version

Q91VR7 A2AVS1 Q9DC74 (UniProt | EBI)

Last sequence update: 2001-12-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Microtubule-associated proteins 1A/1B light chain 3A {ECO:0000305};AltName: Full=Autophagy-related protein LC3 A;AltName: Full=Autophagy-related ubiquitin-like modifier LC3 A;AltName: Full=MAP1 light chain 3-like protein 1;AltName: Full=MAP1

Provider

SWISS-PROT

Sequence

Polypeptide 121 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Map1lc3a	microtubule-associated protein 1 light chain 3 alpha	59	125	3	4

Sequence references in MGI

J:70539 Mizushima N, et al., Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J Cell Biol. 2001 Feb 19;152(4):657-68
J:87279 Hemelaar J, et al., A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L. J Biol Chem. 2003 Dec 19;278(51):51841-50
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:313627 Reggio A, et al., Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control. EMBO Rep. 2021 Sep 6;22(9):e52289
J:313858 Tamargo-Gomez I, et al., ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration. Cell Death Differ. 2021 Sep;28(9):2651-2672