Sequence Detail

ID/Version

Q91XA9 Q9D803 A0T468 B8K282 Q99PH2 Q3TVE7 Q9JLN1 (UniProt | EBI)

Last sequence update: 2003-10-24
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Acidic mammalian chitinase; Short=AMCase; EC=3.2.1.14;AltName: Full=YNL;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 473 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Chia1	chitinase, acidic 1	26	99	6	13

Sequence references in MGI

J:67724 Boot RG, et al., Identification of a novel acidic mammalian chitinase distinct from chitotriosidase. J Biol Chem. 2001 Mar 2;276(9):6770-8
J:81266 Suzuki M, et al., Cellular expression of gut chitinase mRNA in the gastrointestinal tract of mice and chickens. J Histochem Cytochem. 2002 Aug;50(8):1081-9
J:91569 Zhu Z, et al., Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science. 2004 Jun 11;304(5677):1678-82
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:133315 Bussink AP, et al., A single histidine residue modulates enzymatic activity in acidic mammalian chitinase. FEBS Lett. 2008 Mar 19;582(6):931-5
J:143316 Hartl D, et al., Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells. J Biol Chem. 2008 Nov 28;283(48):33472-82
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89