Sequence Detail

ID/Version

Q91YE2 Q99MI0 Q8VHJ1 Q8C6I4 Q8CIL9 (UniProt | EBI)

Last sequence update: 2003-06-16
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Prolyl hydroxylase EGLN2 {ECO:0000305}; EC=1.14.11.- {ECO:0000305|PubMed:24809345};AltName: Full=Egl nine homolog 2 {ECO:0000305}; EC=1.14.11.29 {ECO:0000250|UniProtKB:Q96KS0, ECO:0000255|PROSITE-ProRule:PRU00805};AltName: Fu

Provider

SWISS-PROT

Sequence

Polypeptide 419 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Egln2	egl-9 family hypoxia-inducible factor 2	32	100	3	22

Sequence references in MGI

J:72041 Taylor MS, Characterization and comparative analysis of the EGLN gene family. Gene. 2001 Sep 5;275(1):125-32
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:132630 Aragones J, et al., Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat Genet. 2008 Feb;40(2):170-80
J:232292 Scortegagna M, et al., Fine tuning of the UPR by the ubiquitin ligases Siah1/2. PLoS Genet. 2014 May;10(5):e1004348
J:306780 Adluri RS, et al., Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-/-) attenuates ex vivo myocardial ischemia/reperfusion injury through hypoxia-inducible factor-1alpha transcription factor and its target genes in mice. Antioxid Redox Signal. 2011 Oct 1;15(7):1789-97