ID/Version |
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Sequence description from provider |
RecName: Full=Protein THEMIS2 {ECO:0000305};AltName: Full=Induced by contact to basement membrane 1 protein {ECO:0000303|PubMed:20644716}; Short=Protein ICB-1;AltName: Full=Thymocyte-expressed molecule involved in selection protein 2; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
663
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:99680
The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:151074 Fu G, et al., Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling. Nat Immunol. 2009 Aug;10(8):848-56 J:151076 Johnson AL, et al., Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection. Nat Immunol. 2009 Aug;10(8):831-9 J:189787 Lesourne R, et al., Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function. J Immunol. 2012 Aug 1;189(3):1154-61 J:232061 Hartweger H, et al., Themis2 is not required for B cell development, activation, and antibody responses. J Immunol. 2014 Jul 15;193(2):700-7 J:259481 Cheng D, et al., Themis2 lowers the threshold for B cell activation during positive selection. Nat Immunol. 2017 Feb;18(2):205-213 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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