Sequence Detail

ID/Version

Q91ZE0 Q3TSX6 Q3UMX1 Q91XH1 (UniProt | EBI)

Last sequence update: 2002-06-20
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Trimethyllysine dioxygenase, mitochondrial; EC=1.14.11.8 {ECO:0000250|UniProtKB:Q9NVH6};AltName: Full=Epsilon-trimethyllysine 2-oxoglutarate dioxygenase;AltName: Full=TML hydroxylase;AltName: Full=TML-alpha-ketoglutarate dioxygenase;

Provider

SWISS-PROT

Sequence

Polypeptide 421 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tmlhe	trimethyllysine hydroxylase, epsilon	16	2	3	4

Sequence references in MGI

J:76186 Vaz FM, et al., Molecular and Biochemical Characterization of Rat epsilon -N-Trimethyllysine Hydroxylase, the First Enzyme of Carnitine Biosynthesis. J Biol Chem. 2001 Sep 7;276(36):33512-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121424 Monfregola J, et al., Functional characterization of the TMLH gene: promoter analysis, in situ hybridization, identification and mapping of alternative splicing variants. Gene. 2007 Jun 15;395(1-2):86-97
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89