Sequence Detail

ID/Version

Q91ZJ0 Q8R356 (UniProt | EBI)

Last sequence update: 2008-02-05
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Crossover junction endonuclease MUS81; EC=3.1.22.-;

Provider

SWISS-PROT

Sequence

Polypeptide 551 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mus81	MUS81 structure-specific endonuclease subunit	30	96	3	24

Sequence references in MGI

J:72909 Chen XB, et al., Human Mus81-associated endonuclease cleaves Holliday junctions in vitro. Mol Cell. 2001 Nov;8(5):1117-27
J:91570 McPherson JP, et al., Involvement of mammalian Mus81 in genome integrity and tumor suppression. Science. 2004 Jun 18;304(5678):1822-6
J:100407 Dendouga N, et al., Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis. Mol Cell Biol. 2005 Sep;25(17):7569-79
J:235782 Braun J, et al., The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis. PLoS One. 2016;11(3):e0152278