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Sequence Detail
ID/Version
Q922G7 Q9WVR0 (UniProt | EBI) Last sequence update: 2001-12-01
Last annotation update: 2024-11-27
Sequence
description
from provider
RecName: Full=Tektin-2;AltName: Full=Tektin-t;AltName: Full=Testicular tektin;
Provider SWISS-PROT
Sequence
Polypeptide 430 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Tekt2 tektin 2 11 100 3 9
Sequence references in MGI J:56926 Iguchi N, et al., Molecular cloning of haploid germ cell-specific tektin cDNA and analysis of the protein in mouse testis. FEBS Lett. 1999 Aug 6;456(2):315-21
J:92779 Tanaka H, et al., Mice deficient in the axonemal protein Tektin-t exhibit male infertility and immotile-cilium syndrome due to impaired inner arm dynein function. Mol Cell Biol. 2004 Sep;24(18):7958-64
J:241053 Yamaguchi A, et al., Molecular cloning and subcellular localization of Tektin2-binding protein 1 (Ccdc 172) in rat spermatozoa. J Histochem Cytochem. 2014 Apr;62(4):286-97
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:324488 Zhang J, et al., TMPRSS12 Functions in Meiosis and Spermiogenesis and Is Required for Male Fertility in Mice. Front Cell Dev Biol. 2022;10:757042
J:333155 Zhang X, et al., Loss-of-function mutations in CEP78 cause male infertility in humans and mice. Sci Adv. 2022 Oct 7;8(40):eabn0968
J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19
J:342625 Chen Z, et al., De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell. 2023 Nov 9;186(23):5041-5053.e19
J:352387 Tai L, et al., In-cell structural insight into the stability of sperm microtubule doublet. Cell Discov. 2023 Nov 21;9(1):116

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory