Sequence Detail

ID/Version

Q925K9 Q5RL09 Q8C625 (UniProt | EBI)

Last sequence update: 2001-12-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Testis-specific serine/threonine-protein kinase 6; Short=TSK-6; Short=TSSK-6; Short=Testis-specific kinase 6; EC=2.7.11.1 {ECO:0000269|PubMed:15870294, ECO:0000269|PubMed:23599433};AltName: Full=Serine/threoni

Provider

SWISS-PROT

Sequence

Polypeptide 273 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tssk6	testis-specific serine kinase 6	41	96	3	3

Sequence references in MGI

J:98891 Spiridonov NA, et al., Identification and characterization of SSTK, a serine/threonine protein kinase essential for male fertility. Mol Cell Biol. 2005 May;25(10):4250-61
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:253146 Jha KN, et al., TSSK6 is required for gammaH2AX formation and the histone-to-protamine transition during spermiogenesis. J Cell Sci. 2017 May 15;130(10):1835-1844
J:263437 Jha KN, et al., Heat shock protein 90 functions to stabilize and activate the testis-specific serine/threonine kinases, a family of kinases essential for male fertility. J Biol Chem. 2013 Jun 7;288(23):16308-20
J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19