Sequence Detail

ID/Version

Q925Q3 Q3U067 Q80XM7 (UniProt | EBI)

Last sequence update: 2006-01-10
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Mitochondrial sodium/calcium exchanger protein {ECO:0000305};AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein 6 {ECO:0000303|PubMed:14625281};AltName: Full=Sodium/calcium exchanger protein, mitochondrial {ECO:0000303|PubMed:20018762};AltName

Provider

SWISS-PROT

Sequence

Polypeptide 585 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc8b1	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1	42	98	3	25

Sequence references in MGI

J:77001 Perelygin AA, et al., Positional cloning of the murine flavivirus resistance gene. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9322-7
J:88504 Cai X, et al., Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6. J Biol Chem. 2004 Feb 13;279(7):5867-76
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:156453 Palty R, et al., NCLX is an essential component of mitochondrial Na+/Ca2+ exchange. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):436-41
J:241464 Kim B, et al., Roles of the mitochondrial Na(+)-Ca(2+) exchanger, NCLX, in B lymphocyte chemotaxis. Sci Rep. 2016 Jun 22;6:28378
J:241472 Takeuchi A, et al., The mitochondrial Na+-Ca2+ exchanger, NCLX, regulates automaticity of HL-1 cardiomyocytes. Sci Rep. 2013 Sep 26;3:2766
J:241501 Luongo TS, et al., The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability. Nature. 2017 May 04;545(7652):93-97