Sequence Detail

ID/Version

Q99MD6 Q9CZE5 (UniProt | EBI)

Last sequence update: 2013-05-29
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Thioredoxin reductase 3; EC=1.8.1.9;AltName: Full=Thioredoxin and glutathione reductase;AltName: Full=Thioredoxin reductase TR2;

Provider

SWISS-PROT

Sequence

Polypeptide 652 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Txnrd3	thioredoxin reductase 3	18	100	3	8

Sequence references in MGI

J:57020 Sun QA, et al., Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases. J Biol Chem. 1999 Aug 27;274(35):24522-30
J:78793 Sun QA, et al., Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3673-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100840 Su D, et al., Mammalian selenoprotein thioredoxin-glutathione reductase. Roles in disulfide bond formation and sperm maturation. J Biol Chem. 2005 Jul 15;280(28):26491-8
J:105604 Sun QA, et al., Reaction mechanism and regulation of mammalian thioredoxin/glutathione reductase. Biochemistry. 2005 Nov 8;44(44):14528-37
J:161674 Gerashchenko MV, et al., CUG start codon generates thioredoxin/glutathione reductase isoforms in mouse testes. J Biol Chem. 2010 Feb 12;285(7):4595-602
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87