Sequence Detail

ID/Version

Q99MJ6 Q8BWE5 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF4 {ECO:0000305}; Short=NHERF-4;AltName: Full=Natrium-phosphate cotransporter IIa C-terminal-associated protein 2; Short=Na/Pi cotransporter C-terminal-associated protein 2;

Provider

SWISS-PROT

Sequence

Polypeptide 498 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nherf4	NHERF family PDZ scaffold protein 4	19	96	4	5

Sequence references in MGI

J:74952 Gisler SM, et al., Interaction of the type IIa Na/Pi cotransporter with PDZ proteins. J Biol Chem. 2001 Mar 23;276(12):9206-13
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:148436 Zachos NC, et al., Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4) dependent mechanism. Cell Physiol Biochem. 2008;22(5-6):693-704
J:243462 Pouly D, et al., USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level. PLoS One. 2016;11(1):e0145155
J:333132 Lee JH, et al., Regulation of SLC26A3 activity by NHERF4 PDZ-mediated interaction. Cell Signal. 2012 Sep;24(9):1821-30