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Sequence Detail
ID/Version
Q99MV2 Q7TPF0 (UniProt | EBI) Last sequence update: 2001-06-01
Last annotation update: 2024-05-29
Sequence
description
from provider
RecName: Full=Testis-expressed protein 19.1 {ECO:0000305}; Short=mTex19.1;AltName: Full=Testis-expressed protein 19A;
Provider SWISS-PROT
Sequence
Polypeptide 351 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Tex19.1 testis expressed gene 19.1 30 108 2 14
Sequence references in MGI J:68614 Wang PJ, et al., An abundance of X-linked genes expressed in spermatogonia. Nat Genet. 2001 Apr;27(4):422-6
J:133713 Kuntz S, et al., Tex19, a mammalian-specific protein with a restricted expression in pluripotent stem cells and germ line. Stem Cells. 2008 Mar;26(3):734-44
J:159793 Ollinger R, et al., Deletion of the pluripotency-associated Tex19.1 gene causes activation of endogenous retroviruses and defective spermatogenesis in mice. PLoS Genet. 2008;4(9):e1000199
J:166982 Yang F, et al., The ubiquitin ligase Ubr2, a recognition E3 component of the N-end rule pathway, stabilizes Tex19.1 during spermatogenesis. PLoS One. 2010;5(11):e14017
J:186276 Celebi C, et al., Tex 19 Paralogs Exhibit a Gonad and Placenta-Specific Expression in the Mouse. J Reprod Dev. 2012 Jul 3;58(3):360-5
J:194978 Reichmann J, et al., The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice. Hum Mol Genet. 2013 May 1;22(9):1791-806
J:198685 Tarabay Y, et al., The mammalian-specific Tex19.1 gene plays an essential role in spermatogenesis and placenta-supported development. Hum Reprod. 2013 Aug;28(8):2201-14
J:243410 Crichton JH, et al., Tex19.1 promotes Spo11-dependent meiotic recombination in mouse spermatocytes. PLoS Genet. 2017 Jul;13(7):e1006904
J:243444 Tarabay Y, et al., Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression. J Cell Sci. 2017 Apr 15;130(8):1463-1474
J:244182 MacLennan M, et al., Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells. Elife. 2017 Aug 14;6:e26152

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory