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Sequence Detail
ID/Version
Q99P68 Q9D3L7 B2RQA5 (UniProt | EBI) Last sequence update: 2019-04-10
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Sclerostin {ECO:0000303|PubMed:15778503};Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 211 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Sost sclerostin 38 119 3 25
Sequence references in MGI J:67858 Brunkow M, et al., Bone dysplasia sclerosteosis results from loss of the sost gene product, a novel cystine knot-containing protein. Am J Hum Genet. 2001 Mar;68(3):577-89
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:168665 Lin C, et al., Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling. J Bone Miner Res. 2009 Oct;24(10):1651-61

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory