Sequence Detail

ID/Version

Q9CPU0 Q543L3 Q8R3T1 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Lactoylglutathione lyase; EC=4.4.1.5 {ECO:0000269|PubMed:18695250};AltName: Full=Aldoketomutase;AltName: Full=Glyoxalase I; Short=Glx I;AltName: Full=Ketone-aldehyde mutase;AltName: Full=Methylglyoxalase;AltName: Full=S-D-lac

Provider

SWISS-PROT

Sequence

Polypeptide 184 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Glo1	glyoxalase 1	23	102	3	11

Sequence references in MGI

J:98728 Kromer SA, et al., Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety. J Neurosci. 2005 Apr 27;25(17):4375-84
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:203406 Kawatani M, et al., The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11691-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89