Sequence Detail

ID/Version

Q9CQ45 Q5TM91 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Neudesin;AltName: Full=Neuron-derived neurotrophic factor;AltName: Full=Secreted protein of unknown function; Short=SPUF protein;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 171 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nenf	neuron derived neurotrophic factor	17	100	3	5

Sequence references in MGI

J:96847 Kimura I, et al., Neudesin, a novel secreted protein with a unique primary structure and neurotrophic activity. J Neurosci Res. 2005 Feb 1;79(3):287-94
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:109511 Kimura I, et al., Neudesin, a secreted factor, promotes neural cell proliferation and neuronal differentiation in mouse neural precursor cells. J Neurosci Res. 2006 Jun;83(8):1415-24
J:132149 Kimura I, et al., Neurotrophic activity of neudesin, a novel extracellular heme-binding protein, is dependent on the binding of heme to its cytochrome b5-like heme/steroid-binding domain. J Biol Chem. 2008 Feb 15;283(7):4323-31
J:198522 Byerly MS, et al., Identification of hypothalamic neuron-derived neurotrophic factor as a novel factor modulating appetite. Am J Physiol Regul Integr Comp Physiol. 2013 Jun;304(12):R1085-95
J:282679 Moutaoufik MT, et al., Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis. iScience. 2019 Sep 27;19:1114-1132
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89