Sequence Detail

ID/Version

Q9CQ73 Q3TIY5 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Plakophilin-2 {ECO:0000312|MGI:MGI:1914701};

Provider

SWISS-PROT

Sequence

Polypeptide 795 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pkp2	plakophilin 2	79	99	3	11

Sequence references in MGI

J:93314 Grossmann KS, et al., Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation. J Cell Biol. 2004 Nov 11;167(1):149-60
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:124009 Goossens S, et al., A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs. J Cell Sci. 2007 Jun 15;120(Pt 12):2126-36
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:337416 Perez-Hernandez M, et al., Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC. Circulation. 2022 Sep 13;146(11):851-867