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Sequence Detail
ID/Version
Q9CQW9 Q9D8L6 (UniProt | EBI) Last sequence update: 2001-06-01
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Interferon-induced transmembrane protein 3 {ECO:0000305};AltName: Full=Dispanin subfamily A member 2b; Short=DSPA2b;AltName: Full=Fragilis protein;AltName: Full=Interferon-inducible protein 15;AltName: Full=Mouse ifitm-like protein 1
Provider SWISS-PROT
Sequence
Polypeptide 137 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ifitm3 interferon induced transmembrane protein 3 38 121 4 24
Sequence references in MGI J:78127 Saitou M, et al., A molecular programme for the specification of germ cell fate in mice. Nature. 2002 Jul 18;418(6895):293-300
J:82212 Tanaka SS, et al., Developmentally regulated expression of mil-1 and mil-2, mouse interferon-induced transmembrane protein like genes, during formation and differentiation of primordial germ cells. Mech Dev. 2002 Dec;119 Suppl 1:S261-7
J:87010 Lange UC, et al., The fragilis interferon-inducible gene family of transmembrane proteins is associated with germ cell specification in mice. BMC Dev Biol. 2003 Mar 19;3(1):1
J:90707 Ropolo A, et al., Cloning of IP15, a pancreatitis-induced gene whose expression inhibits cell growth. Biochem Biophys Res Commun. 2004 Jul 2;319(3):1001-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104972 Tanaka SS, et al., IFITM/Mil/fragilis family proteins IFITM1 and IFITM3 play distinct roles in mouse primordial germ cell homing and repulsion. Dev Cell. 2005 Dec;9(6):745-56
J:137940 Lange UC, et al., Normal germ line establishment in mice carrying a deletion of the Ifitm/Fragilis gene family cluster. Mol Cell Biol. 2008 Aug;28(15):4688-96
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:183865 Everitt AR, et al., IFITM3 restricts the morbidity and mortality associated with influenza. Nature. 2012 Apr 26;484(7395):519-23
J:187558 Huang IC, et al., Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus. PLoS Pathog. 2011;7(1):e1001258
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory