Sequence Detail

ID/Version

Q9CX80 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Cytoglobin {ECO:0000303|PubMed:11919282};AltName: Full=Nitric oxygen dioxygenase {ECO:0000305|PubMed:33334890}; EC=1.14.12.- {ECO:0000269|PubMed:33334890};AltName: Full=Nitrite reductase CYGB {ECO:0000250|UniProtKB:Q8WWM9}; E

Provider

SWISS-PROT

Sequence

Polypeptide 190 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cygb	cytoglobin	49	103	4	9

Sequence references in MGI

J:75784 Burmester T, et al., Cytoglobin: A Novel Globin Type Ubiquitously Expressed inVertebrate Tissues. Mol Biol Evol. 2002 Apr;19(4):416-21
J:89005 Schmidt M, et al., Cytoglobin is a respiratory protein in connective tissue and neurons, which is up-regulated by hypoxia. J Biol Chem. 2004 Feb 27;279(9):8063-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:148613 Halligan KE, et al., Cytoglobin Is Expressed in the Vasculature and Regulates Cell Respiration and Proliferation via Nitric Oxide Dioxygenation. J Biol Chem. 2009 Mar 27;284(13):8539-47
J:249688 Liu X, et al., Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall. Nat Commun. 2017 Apr 10;8:14807
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:345004 Ilangovan G, et al., Defining the reducing system of the NO dioxygenase cytoglobin in vascular smooth muscle cells and its critical role in regulating cellular NO decay. J Biol Chem. 2021 Jan-Jun;296:100196
J:345134 Zweier JL, et al., Cytoglobin has potent superoxide dismutase function. Proc Natl Acad Sci U S A. 2021 Dec 28;118(52)