Sequence Detail

ID/Version

Q9CXZ1 Q9WUB1 (UniProt | EBI)

Last sequence update: 2004-05-10
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial;AltName: Full=Complex I-18 kDa; Short=CI-18 kDa;AltName: Full=Complex I-AQDQ; Short=CI-AQDQ;AltName: Full=NADH-ubiquinone oxidoreductase 18 kDa subunit;Flag

Provider

SWISS-PROT

Sequence

Polypeptide 175 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ndufs4	NADH:ubiquinone oxidoreductase core subunit S4	44	98	3	50

Sequence references in MGI

J:54917 Murdock DG, et al., Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart/muscle isoform of the adenine nucleotide translocator. J Biol Chem. 1999 May 14;274(20):14429-33
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:134334 Kruse SE, et al., Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy. Cell Metab. 2008 Apr;7(4):312-20
J:219580 Liu L, et al., Glial lipid droplets and ROS induced by mitochondrial defects promote neurodegeneration. Cell. 2015 Jan 15;160(1-2):177-90
J:279128 Bolea I, et al., Defined neuronal populations drive fatal phenotype in a mouse model of Leigh syndrome. Elife. 2019 Aug 12;8:e47163
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071