Sequence Detail

ID/Version

Q9CY34 Q9D8K7 Q99JK3 Q9D8K0 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=NEDD8-conjugating enzyme UBE2F; EC=2.3.2.34 {ECO:0000269|PubMed:19250909};AltName: Full=NEDD8 carrier protein UBE2F;AltName: Full=NEDD8 protein ligase UBE2F;AltName: Full=NEDD8-conjugating enzyme 2;AltName: Full=RING-type E3 NEDD8 tr

Provider

SWISS-PROT

Sequence

Polypeptide 185 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ube2f	ubiquitin-conjugating enzyme E2F (putative)	12	96	3	14

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:149160 Huang DT, et al., E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. Mol Cell. 2009 Feb 27;33(4):483-95
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:348744 Chang Y, et al., The UBE2F-CRL5(ASB11)-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells. Dev Cell. 2024 May 20;59(10):1317-1332.e5