Sequence Detail

ID/Version

Q9D099 Q542R2 Q9D0X4 Q9D3J4 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Alkaline ceramidase 3; Short=AlkCDase 3; Short=Alkaline CDase 3; EC=3.5.1.- {ECO:0000269|PubMed:26474409}; EC=3.5.1.23 {ECO:0000269|PubMed:26474409};AltName: Full=Alkaline phytoceramidase; Short=aPHC;

Provider

SWISS-PROT

Sequence

Polypeptide 267 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Acer3	alkaline ceramidase 3	29	99	3	12

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:228886 Wang K, et al., Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain. PLoS Genet. 2015 Oct;11(10):e1005591
J:252108 Wang K, et al., Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system. Cell Death Dis. 2016 Mar 3;7:e2124