Sequence Detail

ID/Version

Q9D0U6 Q91W84 Q3U4U3 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Repressor of RNA polymerase III transcription MAF1 homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 258 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Maf1	MAF1 homolog, negative regulator of RNA polymerase III	27	97	4	10

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:175339 Kantidakis T, et al., mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11823-8
J:222253 Bonhoure N, et al., Loss of the RNA polymerase III repressor MAF1 confers obesity resistance. Genes Dev. 2015 May 1;29(9):934-47
J:269014 Willis IM, et al., Metabolic programming a lean phenotype by deregulation of RNA polymerase III. Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):12182-12187