Sequence Detail

ID/Version

Q9D1N2 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 {ECO:0000303|PubMed:12496272}; Short=GPI-HBP1 {ECO:0000303|PubMed:12496272}; Short=GPI-anchored HDL-binding protein 1 {ECO:0000303|PubMed:124962

Provider

SWISS-PROT

Sequence

Polypeptide 228 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gpihbp1	GPI-anchored HDL-binding protein 1	40	97	2	13

Sequence references in MGI

J:82140 Ioka RX, et al., Expression cloning and characterization of a novel glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein, GPI-HBP1. J Biol Chem. 2003 Feb 28;278(9):7344-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:129764 Beigneux AP, et al., Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. Cell Metab. 2007 Apr;5(4):279-91
J:137557 Beigneux AP, et al., Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase. J Lipid Res. 2008 Jun;49(6):1312-21
J:162997 Davies BS, et al., GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries. Cell Metab. 2010 Jul 4;12(1):42-52
J:214777 Goulbourne CN, et al., The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries. Cell Metab. 2014 May 6;19(5):849-60
J:237922 Allan CM, et al., Mobility of "HSPG-bound" LPL explains how LPL is able to reach GPIHBP1 on capillaries. J Lipid Res. 2017 Jan;58(1):216-225
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89