Sequence Detail

ID/Version

Q9D328 Q9DB64 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Novel acetylcholine receptor chaperone {ECO:0000303|PubMed:26875622, ECO:0000303|PubMed:28445721, ECO:0000303|PubMed:32204458, ECO:0000303|PubMed:32783947, ECO:0000303|PubMed:33422618};AltName: Full=Peroxisomal membrane protein 52; S

Provider

SWISS-PROT

Sequence

Polypeptide 167 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tmem35a	transmembrane protein 35A	21	104	3	9

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:175165 Wiese S, et al., Proteomics characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling. Mol Cell Proteomics. 2007 Dec;6(12):2045-57
J:244268 Kennedy BC, et al., Deletion of novel protein TMEM35 alters stress-related functions and impairs long-term memory in mice. Am J Physiol Regul Integr Comp Physiol. 2016 Jul 01;311(1):R166-78
J:254346 Matta JA, et al., NACHO Mediates Nicotinic Acetylcholine Receptor Function throughout the Brain. Cell Rep. 2017 Apr 25;19(4):688-696
J:260443 Gu S, et al., Brain alpha7 Nicotinic Acetylcholine Receptor Assembly Requires NACHO. Neuron. 2016 Mar 2;89(5):948-55
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:304046 Deshpande A, et al., Why Does Knocking Out NACHO, But Not RIC3, Completely Block Expression of alpha7 Nicotinic Receptors in Mouse Brain?. Biomolecules. 2020 Mar 19;10(3):470
J:304156 Kweon HJ, et al., NACHO Engages N-Glycosylation ER Chaperone Pathways for alpha7 Nicotinic Receptor Assembly. Cell Rep. 2020 Aug 11;32(6):108025
J:305347 Khasabov SG, et al., The nAChR Chaperone TMEM35a (NACHO) Contributes to the Development of Hyperalgesia in Mice. Neuroscience. 2021 Mar 1;457:74-87