Sequence Detail

ID/Version

Q9D513 E9QLG1 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Meiosis-specific with OB domain-containing protein {ECO:0000305}; EC=3.1.-.-;AltName: Full=Protein expressed in male leptotene and zygotene spermatocytes 675; Short=MLZ-675;

Provider

SWISS-PROT

Sequence

Polypeptide 470 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Meiob	meiosis specific with OB domains	21	103	4	14

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:187568 Kogo H, et al., Screening of genes involved in chromosome segregation during meiosis I: toward the identification of genes responsible for infertility in humans. J Hum Genet. 2010 May;55(5):293-9
J:203426 Souquet B, et al., MEIOB targets single-strand DNA and is necessary for meiotic recombination. PLoS Genet. 2013;9(9):e1003784
J:204663 Luo M, et al., MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination. Nat Commun. 2013;4:2788
J:292036 Zhang J, et al., The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells. Nat Commun. 2020 Apr 28;11(1):2055