Sequence Detail

ID/Version

Q9D7Z6 Q8R049 O88826 (UniProt | EBI)

Last sequence update: 2001-12-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Calcium-activated chloride channel regulator 1; EC=3.4.-.- {ECO:0000250|UniProtKB:A8K7I4};AltName: Full=Calcium-activated chloride channel family member 3; Short=mCLCA3;AltName: Full=Protein gob-5;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 913 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Clca1	chloride channel accessory 1	25	105	3	8

Sequence references in MGI

J:53044 Komiya T, et al., Cloning and identification of the gene gob-5, which is expressed in intestinal goblet cells in mice. Biochem Biophys Res Commun. 1999 Feb 16;255(2):347-51
J:76668 Leverkoehne I, et al., The murine mCLCA3 (alias gob-5) protein is located in the mucin granule membranes of intestinal, respiratory, and uterine goblet cells. J Histochem Cytochem. 2002 Jun;50(6):829-38
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100887 Gibson A, et al., hCLCA1 and mCLCA3 are secreted non-integral membrane proteins and therefore are not ion channels. J Biol Chem. 2005 Jul 22;280(29):27205-12
J:125158 Long AJ, et al., Gob-5 contributes to goblet cell hyperplasia and modulates pulmonary tissue inflammation. Am J Respir Cell Mol Biol. 2006 Sep;35(3):357-65