Sequence Detail

ID/Version

Q9DB77 Q8BK11 Q9CVK7 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Cytochrome b-c1 complex subunit 2, mitochondrial;AltName: Full=Complex III subunit 2;AltName: Full=Core protein II;AltName: Full=Ubiquinol-cytochrome-c reductase complex core protein 2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 453 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Uqcrc2	ubiquinol cytochrome c reductase core protein 2	25	114	4	7

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:142191 Acin-Perez R, et al., Respiratory active mitochondrial supercomplexes. Mol Cell. 2008 Nov 21;32(4):529-39
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:282679 Moutaoufik MT, et al., Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis. iScience. 2019 Sep 27;19:1114-1132
J:285933 Shan W, et al., Critical role of UQCRC1 in embryo survival, brain ischemic tolerance and normal cognition in mice. Cell Mol Life Sci. 2019 Apr;76(7):1381-1396
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:325962 Makarewich CA, et al., The cardiac-enriched microprotein mitolamban regulates mitochondrial respiratory complex assembly and function in mice. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2120476119
J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
J:357966 Vercellino I, et al., Structure and assembly of the mammalian mitochondrial supercomplex CIII2CIV. Nature. 2021 Oct;598(7880):364-367